The Science Behind ADHD: Brain Function and Neurotransmitters
What Happens in the ADHD Brain?
ADHD is a neurodevelopmental disorder, meaning it stems from differences in brain structure and function. People with ADHD have variations in brain regions that control:
Attention
Executive function
Impulse control
Motivation and reward
These differences explain why focus, organization, and self-control can be challenging.
Key Brain Regions Involved
1. Prefrontal Cortex
Responsible for planning, decision-making, and self-regulation
Often underactive in ADHD, leading to difficulty staying organized and regulating impulses
2. Basal Ganglia
Helps control movement and reward processing
Differences may contribute to hyperactivity and difficulty initiating tasks
3. Cerebellum
Coordinates motor control and attention
Structural differences may affect timing and cognitive control
Neurotransmitters and ADHD
Chemical messengers play a key role:
Dopamine: Regulates motivation, reward, and focus
Norepinephrine: Influences attention, alertness, and arousal
Low or imbalanced levels of these neurotransmitters make it harder to sustain focus and regulate behavior.
Genetics and ADHD
ADHD often runs in families. Multiple genes contribute small increases in risk. Environmental factors like prenatal stress, maternal smoking, or premature birth may also interact with genetics to influence development.
Final Thoughts
ADHD is rooted in biological and neurological differences—it’s not caused by laziness or poor parenting. Understanding the brain science behind ADHD reduces stigma and highlights why treatment and support are effective.